NFkB p100 / p52 Polyclonal Antibody | G-AB-10271
Gentaur Antibodies
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Gentaur Antibodies
NFkB p100 / p52 Polyclonal Antibody | G-AB-10271
- SKU:
- G-AB-10271
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
NFkB p100 / p52 Polyclonal Antibody | G-AB-10271 | Gentaur Antibodies
Overview: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) . The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 4791
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human NFkB p100 / p52 (NP_002493.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q00653
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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