NLRP2 Polyclonal Antibody | G-AB-12103

NLRP2 Polyclonal Antibody | G-AB-12103 | Gentaur Antibodies

Overview: This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD) , a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR) . Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: NLRP2, CLR19.9, NALP2, NBS1, PAN1, PYPAF2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 55655

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human NLRP2 (NP_060322.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NX02

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NLRP2 Polyclonal Antibody DataSheet