NOD1 Polyclonal Antibody | G-AB-07807

NOD1 Polyclonal Antibody | G-AB-07807 | Gentaur Antibodies

Overview: This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD) , a centrally located nucleotide-binding domain (NBD) , and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: NOD1, CARD4, CLR7.1, NLRC1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10392

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human NOD1 (NP_006083.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y239

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NOD1 Polyclonal Antibody DataSheet