NPPC Polyclonal Antibody | G-AB-02905
Gentaur Antibodies
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Gentaur Antibodies
NPPC Polyclonal Antibody | G-AB-02905
- SKU:
- G-AB-02905
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
NPPC Polyclonal Antibody | G-AB-02905 | Gentaur Antibodies
Overview: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Synonyms: ANFC, C type natriuretic peptide precursor, CNP, CNP-53, CNP2, Natriuretic peptide C, Natriuretic peptide precursor C, NPPC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_077720
Clonality: Polyclonal
Immunogen: Synthetic peptide of human NPPC
Clone #:
Conjugation: Unconjugated
Swissprot: P23582
Santa Cruz: sc-21371/sc-21372/sc-20952
Calculated MW:
Observed MW:
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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