NQO1 Polyclonal Antibody | G-AB-08981

NQO1 Polyclonal Antibody | G-AB-08981 | Gentaur Antibodies

Overview: This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD) , an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: DHQU, DIA4, DTD, NMOR1, NMORI, QR1, NQO1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 1728

Accession #:

Clonality:

Immunogen: A synthetic peptide of human NQO1 (NP_000894.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P15559

Santa Cruz:

Calculated MW: 26 kDa/27 kDa/30 kDa

Observed MW: 32 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NQO1 Polyclonal Antibody DataSheet