NRG1 Polyclonal Antibody | G-AB-01717

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€136.92 - €390.60
SKU:
G-AB-01717
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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NRG1 Polyclonal Antibody | G-AB-01717 | Gentaur Antibodies

Overview: The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: Acetylcholine receptor-inducing activity, Acetylcholine receptor-inducing activity, CHICK, homolog of, ARIA, Breast cancer cell differentiation factor p45, GGF, GGF2, Glial growth factor, Heregulin, heregulin, alpha (45kD, ERBB2 p185-activator) , HGL, HRG, HRG1, HRGA, MST131, NDF, Neu differentiation factor, Neuregulin 1, neuregulin 1 type IV beta 1a, neuregulin 1 type IV beta 3, Neuregulin-1, NRG 1, nrg1, NRG1-IT2, NRG1, OTTHUMP00000225398, OTTHUMP00000225419, OTTHUMP00000225420, OTTHUMP00000225421, OTTHUMP00000225422, OTTHUMP00000225477, OTTHUMP00000225545, OTTHUMP00000230603, OTTHUMP00000230605, pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, ProNRG1, Sensory and motor neuron-derived factor, SMDF

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_039258

Clonality: Polyclonal

Immunogen: Synthetic peptide of human NRG1

Clone #:

Conjugation: Unconjugated

Swissprot: Q02297

Santa Cruz: sc-33271/sc-33270/sc-1793/sc-33269/sc-1791/sc-1792/sc-348/sc-537/sc-28916/sc-347

Calculated MW: 70 kDa

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NRG1 Polyclonal Antibody DataSheet

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