NTRK1 Polyclonal Antibody | G-AB-09111

NTRK1 Polyclonal Antibody | G-AB-09111 | Gentaur Antibodies

Overview: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: NTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4914

Accession #:

Clonality:

Immunogen: A synthetic peptide of human NTRK1 (NP_002520.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P04629

Santa Cruz:

Calculated MW: 77 kDa/83 kDa/86 kDa/87 kDa

Observed MW: 140 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NTRK1 Polyclonal Antibody DataSheet