OAS1 Polyclonal Antibody | G-AB-10104

OAS1 Polyclonal Antibody | G-AB-10104 | Gentaur Antibodies

Overview: This gene is induced by interferons and encodes a protein that synthesizes 2', 5'-oligoadenylates (2-5As) . This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: OAS1, E18/E16, IFI-4, OIAS, OIASI

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4938

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human OAS1 (NP_002525.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P00973

Santa Cruz:

Calculated MW: 41 kDa/43 kDa/46 kDa/47 kDa

Observed MW: 40 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

OAS1 Polyclonal Antibody DataSheet