OCT4 Polyclonal Antibody | G-AB-11945
- 3 to 5 Working Days
- Human, Mouse, Rat
OCT4 Polyclonal Antibody | G-AB-11945 | Gentaur Antibodies
Overview: This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells
Synonyms: POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4
Reactivity: Human, Mouse, Rat
Gene ID: 5460
Immunogen: A synthetic peptide of human OCT4
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.