P38 Polyclonal Antibody | G-AB-05921
Gentaur Antibodies
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Gentaur Antibodies
P38 Polyclonal Antibody | G-AB-05921
- SKU:
- G-AB-05921
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
P38 Polyclonal Antibody | G-AB-05921 | Gentaur Antibodies
Overview: Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Immunology, Signal Transduction
Synonyms: CSAID Binding Protein 1, CSAID binding protein, CSAID-binding protein, Csaids binding protein, CSBP 1, CSBP 2, CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, MAX-interacting protein 2, Mitogen Activated Protein Kinase 14, Mitogen activated protein kinase p38 alpha, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, MK14, Mxi 2, MXI2, p38 ALPHA, p38, p38 MAP kinase, p38 MAPK, p38 mitogen activated protein kinase, p38ALPHA, p38alpha Exip, PRKM14, PRKM15, RK, SAPK2A
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #:
Clonality: Polyclonal
Immunogen: Synthesized peptide derived from human p38 around the non-phosphorylation site of Thr180/Tyr182.
Clone #:
Conjugation: Unconjugated
Swissprot: Q16539
Santa Cruz: sc-535, sc-7149, sc-728
Calculated MW: 41 kDa
Observed MW: 38 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: WB, IHC-p, ELISA
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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