p53 Polyclonal Antibody | G-AB-07161
Gentaur Antibodies
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Gentaur Antibodies
p53 Polyclonal Antibody | G-AB-07161
- SKU:
- G-AB-07161
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Rat
p53 Polyclonal Antibody | G-AB-07161 | Gentaur Antibodies
Overview: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: BCC7, LFS1, P53, TRP53, p53, TP53, BMFS5
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 7157
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human p53 (NP_000537.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: P04637
Santa Cruz:
Calculated MW: 23-43 kDa
Observed MW: 53 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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