PARN Polyclonal Antibody | G-AB-11388

PARN Polyclonal Antibody | G-AB-11388 | Gentaur Antibodies

Overview: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly (A) as the substrate, hence, efficiently degrades poly (A) tails of mRNAs. Exonucleolytic degradation of the poly (A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: PARN, DAN, DKCB6, PFBMFT4

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 5073

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PARN (NP_002573.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O95453

Santa Cruz:

Calculated MW: 52 kDa/66 kDa/67 kDa/73 kDa

Observed MW: 73 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PARN Polyclonal Antibody DataSheet