PDHB Polyclonal Antibody | G-AB-11390
- 3 to 5 Working Days
- Human, Mouse, Rat
PDHB Polyclonal Antibody | G-AB-11390 | Gentaur Antibodies
Overview: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1) , dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) . The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction, Tags & Cell Markers
Synonyms: PDHB, PDHBD, PDHE1-B, PHE1B
Reactivity: Human, Mouse, Rat
Gene ID: 5162
Immunogen: Recombinant fusion protein of human PDHB (NP_000916.2) .
Calculated MW: 37 kDa/39 kDa
Observed MW: 39 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.