Perforin Polyclonal Antibody | G-AB-07110

Perforin Polyclonal Antibody | G-AB-07110 | Gentaur Antibodies

Overview: The protein encoded by this gene has structural and functional similarities to complement component 9 (C9) . Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2) , a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: PRF1, FLH2, HPLH2, P1, PFN1, PFP, perforin-1, Perforin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5551

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human Perforin (NP_001076585.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P14222

Santa Cruz:

Calculated MW: 61 kDa

Observed MW: 70 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Perforin Polyclonal Antibody DataSheet