PERK Polyclonal Antibody | G-AB-05972

PERK Polyclonal Antibody | G-AB-05972 | Gentaur Antibodies

Overview: Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2) , leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR) -induced G1 growth arrest due to the loss of cyclin D1.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinase, PEK, PRKR like endoplasmic reticulum kinase, PRKR-like endoplasmic reticulum kinase, WRS

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from the N-terminal region of human PERK

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NZJ5

Santa Cruz:

Calculated MW: 125 kDa

Observed MW: 125 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PERK Polyclonal Antibody DataSheet

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