PEX19 Polyclonal Antibody | G-AB-10675
- 3 to 5 Working Days
- Human, Mouse, Rat
PEX19 Polyclonal Antibody | G-AB-10675 | Gentaur Antibodies
Overview: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS) , as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14) , which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction, Tags & Cell Markers
Synonyms: PEX19, D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1
Reactivity: Human, Mouse, Rat
Gene ID: 5824
Immunogen: Recombinant fusion protein of human PEX19 (NP_002848.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.