PEX3 Polyclonal Antibody | G-AB-11649

PEX3 Polyclonal Antibody | G-AB-11649 | Gentaur Antibodies

Overview: The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS) .

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: PEX3, PBD10A, PBD10B, TRG18

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8504

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PEX3 (NP_003621.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P56589

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PEX3 Polyclonal Antibody DataSheet