Phospho-AMPKα1 (S485) Polyclonal Antibody | G-AB-12608
Gentaur Antibodies
- SKU:
- G-AB-12608
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
Phospho-AMPKα1 (S485) Polyclonal Antibody | G-AB-12608 | Gentaur Antibodies
Overview: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
Synonyms: PRKAA1, AMPK, AMPKa1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5562
Accession #:
Clonality:
Immunogen: A phospho specific peptide corresponding to residues surrounding S485 of human PRKAA1
Clone #:
Conjugation: Unconjugated
Swissprot: Q13131
Santa Cruz:
Calculated MW: 64 kDa/65 kDa
Observed MW: 56 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.