Phospho-AMPKα1 (S485) Polyclonal Antibody | G-AB-12608

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€236.04 - €477.96
SKU:
G-AB-12608
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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Phospho-AMPKα1 (S485) Polyclonal Antibody | G-AB-12608 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms: PRKAA1, AMPK, AMPKa1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5562

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S485 of human PRKAA1

Clone #:

Conjugation: Unconjugated

Swissprot: Q13131

Santa Cruz:

Calculated MW: 64 kDa/65 kDa

Observed MW: 56 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-AMPKα1 (S485) Polyclonal Antibody DataSheet