Phospho-Btk (Y223) Polyclonal Antibody | G-AB-12512
- 3 to 5 Working Days
- Human, Mouse, Rat
Phospho-Btk (Y223) Polyclonal Antibody | G-AB-12512 | Gentaur Antibodies
Overview: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Immunology, Signal Transduction
Synonyms: AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA, BTK
Reactivity: Human, Mouse, Rat
Gene ID: 695
Immunogen: A synthetic phosphorylated peptide around Y223 of human Btk (NP_000052.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:20-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.