Phospho-CFL1 (S3) Polyclonal Antibody | G-AB-12529
Gentaur Antibodies
- SKU:
- G-AB-12529
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
Phospho-CFL1 (S3) Polyclonal Antibody | G-AB-12529 | Gentaur Antibodies
Overview: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction
Synonyms: CFL1, CFL, HEL-S-15, cofilin, cofilin-1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 1072
Accession #:
Clonality:
Immunogen: A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
Clone #:
Conjugation: Unconjugated
Swissprot: P23528
Santa Cruz:
Calculated MW: 18 kDa
Observed MW: 18 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.