Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody | G-AB-05838
Gentaur Antibodies
- SKU:
- G-AB-05838
- Availability:
- 3 to 5 Working Days
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody | G-AB-05838 | Gentaur Antibodies
Overview: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) . Phosphorylates SPZ1 (By similarity) . Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Signal Transduction, Neuroscience
Synonyms: MAPK3, ERK1, PRKM3, Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Gene ID:
Accession #:
Clonality: Monoclonal
Immunogen: Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205)
Clone #: Clone:4D4
Conjugation: Unconjugated
Swissprot: P27361, P28482
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Protein A purification
Application: IHC-p
Dilution: IHC 1:100-200
Storage: Store at -20°C. Avoid freeze / thaw cycles.