Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573

Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573 | Gentaur Antibodies

Overview: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: ESPL1, ESP1, SEPA, separin

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 9700

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q14674

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:20-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-ESPL1 (S1126) Polyclonal Antibody DataSheet