Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573
- 3 to 5 Working Days
Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573 | Gentaur Antibodies
Overview: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: ESPL1, ESP1, SEPA, separin
Gene ID: 9700
Immunogen: A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:20-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.