Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573
Gentaur Antibodies
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Gentaur Antibodies
Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573
- SKU:
- G-AB-12573
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
Phospho-ESPL1 (S1126) Polyclonal Antibody | G-AB-12573 | Gentaur Antibodies
Overview: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: ESPL1, ESP1, SEPA, separin
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 9700
Accession #:
Clonality:
Immunogen: A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q14674
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:20-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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