Phospho-HDAC5 (Ser498) Polyclonal Antibody | G-AB-05749
Gentaur Antibodies
- SKU:
- G-AB-05749
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
Phospho-HDAC5 (Ser498) Polyclonal Antibody | G-AB-05749 | Gentaur Antibodies
Overview: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells
Synonyms: Antigen NY CO 9, Antigen NY-CO-9, HD5, HDAC 5, HDAC5, HDAC5, Histone deacetylase 5, NY CO 9
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #:
Clonality: Polyclonal
Immunogen: Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498
Clone #:
Conjugation: Unconjugated
Swissprot: Q9UQL6
Santa Cruz: sc-5250/sc-11419/sc-5252
Calculated MW: 122 kDa
Observed MW: 122 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: WB, IHC-p, IF, ELISA
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Storage: Store at -20°C. Avoid freeze / thaw cycles.