Phospho-HDAC5 (Ser498) Polyclonal Antibody | G-AB-05749

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$163.00 - $465.00
SKU:
G-AB-05749
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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Phospho-HDAC5 (Ser498) Polyclonal Antibody | G-AB-05749 | Gentaur Antibodies

Overview: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: Antigen NY CO 9, Antigen NY-CO-9, HD5, HDAC 5, HDAC5, HDAC5, Histone deacetylase 5, NY CO 9

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UQL6

Santa Cruz: sc-5250/sc-11419/sc-5252

Calculated MW: 122 kDa

Observed MW: 122 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-HDAC5 (Ser498) Polyclonal Antibody DataSheet