HDAC5 Polyclonal Antibody | G-AB-11548

HDAC5 Polyclonal Antibody | G-AB-11548 | Gentaur Antibodies

Overview: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: HDAC5, HD5, NY-CO-9

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 10014

Accession #:

Clonality:

Immunogen: A synthetic peptide of human HDAC5 (NP_005465.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UQL6

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:20-1:50

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HDAC5 Polyclonal Antibody DataSheet