Phospho-HDAC5 (S498) Polyclonal Antibody | G-AB-12532

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$281.00 - $569.00
3 to 5 Working Days
Human, Mouse, Rat
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Phospho-HDAC5 (S498) Polyclonal Antibody | G-AB-12532 | Gentaur Antibodies

Overview: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: HDAC5, HD5, NY-CO-9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10014

Accession #:


Immunogen: A phospho specific peptide corresponding to residues surrounding S498 of human HDAC5

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UQL6

Santa Cruz:

Calculated MW: 112 kDa/121 kDa/122 kDa

Observed MW: 140 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-HDAC5 (S498) Polyclonal Antibody DataSheet