Phospho-Histone H3 (S10) Polyclonal Antibody | G-AB-12607
- 3 to 5 Working Days
- Human, Mouse, Rat
Phospho-Histone H3 (S10) Polyclonal Antibody | G-AB-12607 | Gentaur Antibodies
Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Category Type: Phosphorylated antibody
Synonyms: H3.4, H3/g, H3FT, H3t, HIST3H3, Histone H3, HIST1H3A
Reactivity: Human, Mouse, Rat
Gene ID: 8290
Immunogen: A synthetic phosphorylated peptide around S10 of human Histone H3 (NP_003484.1) .
Calculated MW: 15 kDa
Observed MW: 17 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.