Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody | G-AB-05753

Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody | G-AB-05753 | Gentaur Antibodies

Overview: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms: I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human IκB-α around the phosphorylation site of Ser32/36

Clone #:

Conjugation: Unconjugated

Swissprot: P25963

Santa Cruz:

Calculated MW: 36 kDa

Observed MW: 34 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody DataSheet