Phospho-Jak3 (Y980/981) Polyclonal Antibody | G-AB-12591

Phospho-Jak3 (Y980/981) Polyclonal Antibody | G-AB-12591 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular Signal Transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3718

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around Y980 of human Jak3 (NP_000206.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P52333

Santa Cruz:

Calculated MW: 68 kDa/121 kDa/125 kDa

Observed MW: 110 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-Jak3 (Y980/981) Polyclonal Antibody DataSheet