Phospho-Jak3 (Y980/981) Polyclonal Antibody | G-AB-12591
- 3 to 5 Working Days
- Human, Mouse, Rat
Phospho-Jak3 (Y980/981) Polyclonal Antibody | G-AB-12591 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular Signal Transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .
Category Type: Phosphorylated antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Reactivity: Human, Mouse, Rat
Gene ID: 3718
Immunogen: A synthetic phosphorylated peptide around Y980 of human Jak3 (NP_000206.2) .
Calculated MW: 68 kDa/121 kDa/125 kDa
Observed MW: 110 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.