Phospho-NF-kB p65 (S536) Polyclonal Antibody | G-AB-12576

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€236.04 - €477.96
SKU:
G-AB-12576
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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Phospho-NF-kB p65 (S536) Polyclonal Antibody | G-AB-12576 | Gentaur Antibodies

Overview: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Neuroscience, Signal Transduction

Synonyms: NFKB3, p65, NF-kB p65, RELA, CMCU

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5970

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S536 of human NF-kB p65

Clone #:

Conjugation: Unconjugated

Swissprot: Q04206

Santa Cruz:

Calculated MW: 58 kDa/59 kDa/60 kDa

Observed MW: 71 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:1000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-NF-kB p65 (S536) Polyclonal Antibody DataSheet