Phospho-PDGFR beta (Y740) Polyclonal Antibody | G-AB-12598
- 3 to 5 Working Days
- Human, Mouse
Phospho-PDGFR beta (Y740) Polyclonal Antibody | G-AB-12598 | Gentaur Antibodies
Overview: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cardiovascular, Signal Transduction
Synonyms: CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT, PDGF Receptor beta, PDGFRB, PDGFR beta
Reactivity: Human, Mouse
Gene ID: 5159
Immunogen: A synthetic phosphorylated peptide around Y740 of human PDGFR beta (NP_002600.1) .
Calculated MW: 37 kDa/123 kDa
Observed MW: 180 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.