Phospho-RB1 (S780) Polyclonal Antibody | G-AB-12564
Gentaur Antibodies
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Gentaur Antibodies
Phospho-RB1 (S780) Polyclonal Antibody | G-AB-12564
- SKU:
- G-AB-12564
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
Phospho-RB1 (S780) Polyclonal Antibody | G-AB-12564 | Gentaur Antibodies
Overview: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) , bladder cancer, and osteogenic sarcoma.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: OSRC, PPP1R130, RB, p105-Rb, pRb, pp110, RB1, Rb
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5925
Accession #:
Clonality:
Immunogen: A phospho specific peptide corresponding to residues surrounding S780 of human RB1
Clone #:
Conjugation: Unconjugated
Swissprot: P06400
Santa Cruz:
Calculated MW: 106 kDa
Observed MW: 100 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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