Phospho-RELA (S468) Polyclonal Antibody | G-AB-12566
- 3 to 5 Working Days
- Human, Mouse
Phospho-RELA (S468) Polyclonal Antibody | G-AB-12566 | Gentaur Antibodies
Overview: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Neuroscience, Signal Transduction
Synonyms: NFKB3, p65, NF-kB p65, RELA, CMCU
Reactivity: Human, Mouse
Gene ID: 5970
Immunogen: A synthetic phosphorylated peptide around S468 of human RELA (NP_001138610.1) .
Calculated MW: 58 kDa/59 kDa/60 kDa
Observed MW: 60 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.