Phospho-RPS6 (S240/244) Polyclonal Antibody | G-AB-12592

Phospho-RPS6 (S240/244) Polyclonal Antibody | G-AB-12592 | Gentaur Antibodies

Overview: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: RPS6, S6, RPS6

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 6194

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around S240 & S244 of human RPS6 (NP_001001.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P62753

Santa Cruz:

Calculated MW: 28 kDa

Observed MW: 36 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-RPS6 (S240/244) Polyclonal Antibody DataSheet