Phospho-STAT1 (Y701) Polyclonal Antibody | G-AB-12519
- 3 to 5 Working Days
Phospho-STAT1 (Y701) Polyclonal Antibody | G-AB-12519 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, STAT1 alpha, STAT1
Gene ID: 6772
Immunogen: A phospho specific peptide corresponding to residues surrounding Y701 of human STAT1
Calculated MW: 83 kDa/87 kDa
Observed MW: 85 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.