PHOX2B Polyclonal Antibody | G-AB-12387

PHOX2B Polyclonal Antibody | G-AB-12387 | Gentaur Antibodies

Overview: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms: PHOX2B, NBLST2, NBPhox, PMX2B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8929

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PHOX2B (NP_003915.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q99453

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PHOX2B Polyclonal Antibody DataSheet