PIDD Polyclonal Antibody | G-AB-10527

PIDD Polyclonal Antibody | G-AB-10527 | Gentaur Antibodies

Overview: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6) -associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD) , and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: PIDD1, LRDD, PIDD

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 55367

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PIDD (NP_665893.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9HB75

Santa Cruz:

Calculated MW: 33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa

Observed MW: 100-110 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PIDD Polyclonal Antibody DataSheet