PIK3C2A Polyclonal Antibody | G-AB-12253
- 3 to 5 Working Days
- Human, Mouse, Rat
PIK3C2A Polyclonal Antibody | G-AB-12253 | Gentaur Antibodies
Overview: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Category Type: Polyclonal Antibody
Research Areas: Immunology, Signal Transduction
Synonyms: PIK3C2A, CPK, PI3-K-C2 (ALPHA) , PI3-K-C2A, PI3K-C2-alpha, PI3K-C2alpha
Reactivity: Human, Mouse, Rat
Gene ID: 5286
Immunogen: Recombinant fusion protein of human PIK3C2A (NP_002636.2) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:100 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.