PLA2G16 Polyclonal Antibody | G-AB-07032

PLA2G16 Polyclonal Antibody | G-AB-07032 | Gentaur Antibodies

Overview: Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa) , and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE) . For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity) . N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.

Category Type: Polyclonal Antibody

Research Areas: Cancer

Synonyms: Adipose specific phospholipase A2, Adipose specific PLA2, Adipose-specific phospholipase A2, AdPLA, Ca independent phospholipase A1/2, Group XVI phospholipase A1/A2, Group XVI phospholipase A2, H rev 107 protein homolog, H REV107 1, H-rev 107 protein homolog, HRAS like suppressor 1, HRAS like suppressor 3, HRAS-like suppressor 1, HRAS-like suppressor 3, HREV107 1, HREV107 3, HREV107, HREV107-1, HREV107-3, HRSL3, HRSL3, Phospholipase A2 group XVI, Pla2g16, Renal carcinoma antigen NY REN 65, Renal carcinoma antigen NY-REN-65

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP009000

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PLA2G16

Clone #:

Conjugation: Unconjugated

Swissprot: P53816

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLA2G16 Polyclonal Antibody DataSheet