PLCG1 Polyclonal Antibody | G-AB-09154

PLCG1 Polyclonal Antibody | G-AB-09154 | Gentaur Antibodies

Overview: The protein encoded by this gene catalyzes the formation of inositol 1, 4, 5-trisphosphate and diacylglycerol from phosphatidylinositol 4, 5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor) -activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5335

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PLCG1 (NP_002651.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P19174

Santa Cruz:

Calculated MW: 148 kDa

Observed MW: 149 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLCG1 Polyclonal Antibody DataSheet