PLEKHG6 Polyclonal Antibody | G-AB-01116

PLEKHG6 Polyclonal Antibody | G-AB-01116 | Gentaur Antibodies

Overview: PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: FLJ10665, MGC126315, MGC126353, MGC126354, Myosin interacting guanine nucleotide exchange factor, PH domain containing family G member 6, Pleckstrin homology domain containing family G (with RhoGef domain) member 6, Pleckstrin homology domain-containing family G member 6, PLEKHG6

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC105961

Clonality: Polyclonal

Immunogen: Recombinant protein of human PLEKHG6

Clone #:

Conjugation: Unconjugated

Swissprot: Q3KR16

Santa Cruz:

Calculated MW: 89 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLEKHG6 Polyclonal Antibody DataSheet