PLGLB2 Polyclonal Antibody | G-AB-06415

PLGLB2 Polyclonal Antibody | G-AB-06415 | Gentaur Antibodies

Overview: Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. PLGLB2 (plasminogen-like B2) , also known as PLGP1, is a 96 amino acid protein that resembles the N-terminal plasminogen activation peptide, which is released from plasminogen during conversion to plasmin. PLGLB2 may bind to lysine binding sites present in the kringle structures of plasminogen, an event that interfers with the binding of fibrin or α-2 antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.

Category Type: Polyclonal Antibody

Research Areas: Immunology, Signal Transduction

Synonyms: Plasminogen-related protein B, PLGB, PLGLB2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC005379

Clonality: Polyclonal

Immunogen: Fusion protein of human PLGLB2

Clone #:

Conjugation: Unconjugated

Swissprot: Q02325

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLGLB2 Polyclonal Antibody DataSheet