PLOD2 Polyclonal Antibody | G-AB-11392

PLOD2 Polyclonal Antibody | G-AB-11392 | Gentaur Antibodies

Overview: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: PLOD2, BRKS2, LH2, TLH

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5352

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PLOD2 (NP_891988.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O00469

Santa Cruz:

Calculated MW: 49 kDa/84 kDa/87 kDa

Observed MW: 85 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLOD2 Polyclonal Antibody DataSheet