PNOC Polyclonal Antibody | G-AB-03261
Gentaur Antibodies
Write a Review
Gentaur Antibodies
PNOC Polyclonal Antibody | G-AB-03261
- SKU:
- G-AB-03261
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
PNOC Polyclonal Antibody | G-AB-03261 | Gentaur Antibodies
Overview: Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids) . Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1) , a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.
Category Type: Polyclonal Antibody
Research Areas: Neuroscience
Synonyms: N/OFQ, N23K, N23K/N27K, Nociceptin, included, nocistatin, Npnc1, OFQ, OFQ/N, Orphanin FQ, Orphanin FQ2, Pnoc, PNOC, ppN/OFQ, PPNOC, pre-pro-N/OFQ, prepronociceptin, pronociceptin, Propronociceptin
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_006219
Clonality: Polyclonal
Immunogen: Synthetic peptide of human PNOC
Clone #:
Conjugation: Unconjugated
Swissprot: Q13519
Santa Cruz: sc-9763/sc-9764/sc-33600
Calculated MW:
Observed MW:
Concentration: 0.4 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Related Products
