PNOC Polyclonal Antibody | G-AB-03261

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€136.92 - €390.60
SKU:
G-AB-03261
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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PNOC Polyclonal Antibody | G-AB-03261 | Gentaur Antibodies

Overview: Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids) . Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1) , a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: N/OFQ, N23K, N23K/N27K, Nociceptin, included, nocistatin, Npnc1, OFQ, OFQ/N, Orphanin FQ, Orphanin FQ2, Pnoc, PNOC, ppN/OFQ, PPNOC, pre-pro-N/OFQ, prepronociceptin, pronociceptin, Propronociceptin

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_006219

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PNOC

Clone #:

Conjugation: Unconjugated

Swissprot: Q13519

Santa Cruz: sc-9763/sc-9764/sc-33600

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PNOC Polyclonal Antibody DataSheet

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