POLH Polyclonal Antibody | G-AB-06478

POLH Polyclonal Antibody | G-AB-06478 | Gentaur Antibodies

Overview: This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: DNA polymerase eta, FLJ16395, FLJ21978, Polh, POLH, polymerase DNA directed eta, RAD30, RAD30 homolog A, RAD30A, Xeroderma pigmentosum variant type protein, XP V, XPV

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC015742

Clonality: Polyclonal

Immunogen: Fusion protein of human POLH

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y253

Santa Cruz:

Calculated MW: 78 kDa

Observed MW: Refer to figures

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

POLH Polyclonal Antibody DataSheet