PPL Polyclonal Antibody | G-AB-11396
- 3 to 5 Working Days
- Human, Mouse, Rat
PPL Polyclonal Antibody | G-AB-11396 | Gentaur Antibodies
Overview: The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
Category Type: Polyclonal Antibody
Research Areas: Immunology, Signal Transduction
Reactivity: Human, Mouse, Rat
Gene ID: 5493
Immunogen: Recombinant fusion protein of human PPL (NP_002696.3) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.