PRMT5 Polyclonal Antibody | G-AB-01378
Gentaur Antibodies
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Gentaur Antibodies
PRMT5 Polyclonal Antibody | G-AB-01378
- SKU:
- G-AB-01378
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
PRMT5 Polyclonal Antibody | G-AB-01378 | Gentaur Antibodies
Overview: Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA) , with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3) ; such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: 72 kDa ICln binding protein, 72 kDa ICln-binding protein, ANM5, Histone synthetic lethal 7, S. cerevisiae, homolog of, Histone-arginine N-methyltransferase PRMT5, HMT1 hnRNP methyltransferase like 5, HOMOLOG OF, SKB1, HRMT1L5, IBP72, Jak-binding protein 1, JBP 1, JBP1, PRMT 5, PRMT5, Protein arginine methyltransferase 5, Protein arginine N methyltransferase 5, Protein arginine N methyltransferase 5 N terminally processed, Protein arginine N-methyltransferase 5, S. POMBE, S. POMBE HOMOLOG OF, SKB1, SHK1 KINASE BINDING PROTEIN 1, Shk1 kinase binding protein 1 homolog, Shk1 kinase-binding protein 1 homolog, Shk1 kinase/binding protein 1, S. pombe, homolog of, SKB 1, SKB1, SKB1 homolog, SKB1: SKB1 homolog (S. pombe) , SKB1Hs
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_001034708
Clonality: Polyclonal
Immunogen: Synthetic peptide of human PRMT5
Clone #:
Conjugation: Unconjugated
Swissprot: O14744
Santa Cruz: sc-22132/sc-136202/sc-292408
Calculated MW: 71 kDa
Observed MW:
Concentration: 0.3 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, ELISA
Dilution: WB 1:200-1:1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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